A safe and effective painkiller, is that possible? Yes it is, it’s called palmitoylethanolamide (or N-(2-Hydroxyethyl)hexadecanamide) and it’s produced by our own body. Palmitoylethanolamide is available in its most pure form as a supplement called PeaCure.
Palmitoylethanolamide (PEA), a bodily fatty acid amine that is available as a supplement, keeps amazing. The substance has earned its status in all types of pain syndromes and. In May 2012 a randomized double-blinded study also revealed positive results towards jaw pain due to arthritis in the jaw, also called arthritis of the temporomandibular joint.
The study proved that this bodily substance is effective and safe. The latter being of specific importance as most other pain medicine is not! Therefore PEA can be called a good and safe pain relief remedy for valid reasons. We quote the authors:
… these results are of particular interest since they confirm the total lack of side effects ascribed to the use of PEA, as demonstrated by clinical studies conducted on a great number of young as well as older adult subjects …
Palmitoylethanolamide against jaw pain and acute pain after pulling a tooth
A few months before, jaw surgeons had already pointed out that palmitoylethanolamide can also be useful for pain after pulling wisdom teeth. 
So now there is a publication about the value of palmitoylethanolamide (PEA) for jaw pain in English language. Not only does the substance work well against jaw pain, the jaw’s ability to open also improved. 
More and more scientific publications about the value of this bodily substance are becoming available, and doctors can no longer ignore the facts. In this new study, PEA, with no notable side effects, also turned out to be superior to conventional medicine, which cause gastrointestinal bleeding and can cause death.
Palmitoylethanolamide: safe and effective and a better alternative than regular pain medicine of the NSAID category
The authors emphasized that:
- PEA is a body’s own substance that protects tissue
- PEA has not notable side effects and can be used over a prolonged period of time
- PEA is important in treating chronic pain
- PEA has a double therapeutic effect. It works as a pain relief and it is anti-inflammatory.
- PEA is an important alternative for the commonly used aspirin-like painkillers (NSAID’s)
The table below clearly shows that PEA was more successful in reducing pain than the painkiller Ibuprofen!
And now the conclusion:
The endogenous nature of PEA and its capacity to act locally and to protect tissues against damage are the premises upon which its therapeutic applications are based:
First, the lack of side effects allows the therapeutic use of PEA for long periods, and this is particularly important for patients manifesting pain associated with chronic diseases and who are already undergoing several debilitating pharmacological therapies.
Secondly, the presence of a double therapeutic effect, anti-inflammatory and antinociceptive, is particularly important for pathologies presenting chronic inflammatory processes such as TMJ or joint OA that continuously stimulate the somatosensory system and induce allodynia and hyperalgesia.
In conclusion, the results of the present study demonstrate that PEA is effective in reducing TMD-related OA and arthralgia pain, thus suggesting its therapeutic use as an alternative tool to ibuprofen.
PEA keeps surprising and is a breakthrough in medicine. In 2012 alone, PEA’s effect became apparent in a number of animal tests, as well as clinical reports, for a plethora of different symptoms that involve pain and inflammation.      
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